Higher Mortality With Severe LV Dysfunction in Patients Without CVD

Background: Left ventricular ejection fraction (LVEF) is the most commonly used method to look at the cardiac function as it is practical, even in mechanically ventilated ICU patients. But most of the studies have looked at mild-to-moderate left ventricular (LV) dysfunction, and not in patients with severely reduced LVEF and their in-hospital mortality in sepsis. Objective: To study the relationship between the severities of LV systolic dysfunction and clinical outcomes and in-hospital mortality in patients with sepsis. Design: Multicenter cohort study. Participants: 2274 patients (age, ≥19 years) with sepsis or septic shock. Methods: Participants underwent echocardiographic examination within 24 hours of sepsis diagnosis. LVEF was categorized as normal (>50%), mild to moderate (30% to 50%), severe ( Results: Median age of participants was 74 years, and 58.6% were male. The LVEF was normal in 1803 patients, mild to moderate in 356 patients, and severe in 115 patients. Of participa more...